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Description
These observations were corroborated by single-cell calcium imaging studies in slices of arcuate nuclei, demonstrating that GLP-1MK-801 inhibits the NMDA-induced intracellular calcium surge relative to GLP-1 alone (Extended Data Fig
Sleep and stress are often overlooked
Semaglutide reduces the *physical* drive to eat, but emotional eating, habit-driven snacking, and food cravings rooted in reward pathways may persist

Serious events like pancreatitis occur in fewer than 1% of users in clinical trials
