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In a phase 2 study, patients with obesity on the highest dose (12 mg) lost an average of about 24% of their body weight in 48 weeks

This energy deficit forces the body to mobilize stored energy reserves while simultaneously adjusting to lower fuel availability, creating temporary fatigue as metabolic efficiency improves

The difference between Wegovy and Mounjaro is in their active ingredients

"This gap between what patients are self-reporting online and what gets captured in trials is really what motivated this whole line of work." Clinical context Dr
