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The American Diabetes Association supports the use of GLP-1 receptor agonists as part of comprehensive diabetes management, particularly in patients requiring weight reduction

Genovese advises

It should be noted that GLP-1-SSM administration did not significantly alter ad libitum blood glucose levels in mice in all the groups (data not shown) suggesting that GLP-1 SSM effects were specific to the anti-inflammatory/anti-diarrheal properties, without any adverse side effects likely to result from free GLP-1 peptide

Several studies point to a protective role of GLP-1RAs on retinal pigment epithelium (RPE) cells, which form the blood-retinal barrier and are vulnerable to inflammation [83, 84]