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Researchers found that participants who took Zepbound for 18 months lost more weight (20.2% of their body weight, or an average of about 50 pounds) compared to those on Wegovy (13.7% of their body weight, or about 33 pounds on average)

Patients must take Rybelsus on an empty stomach, at least 30 minutes before the first food, drink (other than water), or other oral medications of the day

The result was a single peptide with subnanomolar, balanced activity at both incretin receptors and minimal activity at the glucagon receptor 40

Clinically, the results of the injectable and oral formulations are comparable, with the main difference being how the medication enters the bloodstream