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Description
Circulating cytokines and LPS can cross and potentially disrupt the BBB, altering endothelial and astrocytic modulation and increasing cerebral prostaglandin E 2 ( 4.2 -Synuclein pathology and gut-brain propagation Alongside neuroinflammation, PD is defined by the aggregation of Syn into Lewy bodies and neurites ( Preclinical and clinical studies provide further support for gut-to-brain spread

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10.1016/j.eclinm.2024.102782 [DOI] [PMC free article] [PubMed] [Google Scholar] 6.Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JFE, Nauck MA, et al
