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The FDA has issued a warning about some compounded GLP-1 medications that contain semaglutide salts (semaglutide sodium or semaglutide acetate), which are different from the original semaglutide and have safety concerns
A 0.25 mg dose in someone weighing 300 pounds produces lower peak blood concentrations than the same dose in someone weighing 180 pounds

These are all naturally occurring hormones that play a big role in regulating blood sugar, appetite, and metabolism