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These findings indicated that TGF-1 + IL-1 was sufficient to induce fibroblast activation by activating NLRP3 inflammasome, but insufficient to cause NLRP3/caspase-1/GSDMD-mediated fibroblast pyroptosis, while the underlying mechanism remains to be further explored

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doi: 10.7326/M20-0864 58 VermaSBainSCHonoreJBFemJAnMEpRet al

A general caveat when analyzing the tissue distribution of the GLP-1R protein is the lack of sufficiently selective and commercially available antibodies [391]
