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The conversation covers real world effectiveness, side effects, muscle loss concerns, cost and sustainability, and the need for GLP 1 stewardship, including minimum effective dosing, resistance training, and clear plans for tapering when appropriate

Most peptide protocols last about 3 to 6 months, but the exact timeline depends on the peptide used, treatment goal, lab results, response to therapy, and safety monitoring

Insulin secretion and sensitivity after single-dose amisulpride, olanzapine or placebo in young male subjects: double blind, cross-over glucose clamp study

Endocr Rev 18(6):801831
