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Diagnostic evaluation may include: Detailed neurological examination assessing sensation, reflexes, and motor function Hemoglobin A1c measurement to evaluate recent glycemic control Vitamin B12 levels and methylmalonic acid (if B12 is borderline) Serum protein electrophoresis (SPEP) and immunofixation to screen for paraproteinemia Thyroid function tests, as hypothyroidism can contribute to neuropathic symptoms Comprehensive metabolic panel to assess renal and hepatic function Nerve conduction studies in selected cases with atypical features Management strategies focus on optimizing glycemic control, which remains the most evidence-based intervention for preventing and potentially improving diabetic neuropathy

11,2325 EMPA-REG OUTCOME was a randomized, double-blind, placebo-controlled trial involving 7,020 patients with T2D and established cardiovascular disease (CVD)

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177+ patient reviews Hear directly from our patients Frequently asked questions Direct Preventive Care's GLP-1 program offers a comprehensive, medically supervised approach to weight management that goes beyond the typical weight-loss clinic