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Semaglutide requires continued use of medication to maintain weight loss, with prior trials demonstrating discontinuation of medication associated with weight gain within 6 months to 1 year 16

GLB reports receiving research support and steering committee membership from Alnylam, Bayer, Novo Nordisk, Quantum Genomics, and Vascular Dynamics

2019 ESC Guidelines on diabetes, prediabetes, and cardiovascular diseases developed in collaboration with the EASD

Unlike prescription GLP-1 medications where discontinuation can trigger noticeable withdrawal symptoms and appetite rebound, stopping resM is unlikely to produce dramatic changes