how to maintain weight loss after stopping glp 1 GLP-1 effects treatment A new trial suggests a
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It is contraindicated in patients with a personal or family history of medullary thyroid cancers (MTC) or patients with multiple endocrine neoplasia syndrome type 2 (MEN2).[30] FUTURE INDICATIONS AND TRIALS Oral semaglutide has been explored with higher doses of 25 and 50 mg in ongoing PIONEER plus trials.[39] Another trial under the name PIONEER TEEN is ongoing to see the efficacy and safety of semaglutide in children and teenagers with age 10 years to 17 years.[40] PIONEER REAL is a global prospective, non-interventional single-arm real-world study with oral semaglutide.[41] EVOKE and EVOKE plus are ongoing trials to see the effect of oral semaglutide in Alzheimers disease.[42] SOUL is an ongoing CV superiority trial with an objective to prove CV benefits with this molecule
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The Gq agonist MK-2305 drastically improves glucose tolerance and insulin secretion in the KK-Ay mouse model of type 2 diabetes [13]

Fatty liver disease: The combination of diabetes and NAFLD/NASH is effectively addressed by GLP-1 treatment
