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Studies, such as the STEP 4 trial, have shown that while some individuals achieve substantial weight reduction, others may see more modest results due to a combination of factors, including baseline metabolic health, lifestyle habits, and adherence to dietary recommendations

The use of biologic agents that target allergic inflammation has revolutionized the treatment of people who do not have full responses to the standard inhalational therapy mentioned above, yet there are still patients who have uncontrolled disease