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Additionally, in SH-SY5Y neuroblastoma cells, exendin-4 treatment upregulates the mitochondrial quality control regulators Parkin and PTEN induced kinase 1, reduces Bax expression, enhances Akt and Bcl-2 levels, and inhibits tumor cell apoptosis (83)

Higher GLP-1 numbers leads to a higher insulin level, which leads to a higher uptake of glucose

Design of novel exendin-based dual glucagon-like peptide 1 (GLP-1)/glucagon receptor agonists

Lee, whose work involves obesity medicine, also said that clinicians need to be mindful when it comes to possible candidates for these medications who have a previous history of gastrointestinal issues