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Michael Whalen, MD, is an Associate Professor of Urology, Chief of Urologic Oncology, and Director of the Genitourinary Multidisciplinary Clinic at the George Washington University

Parkinsonism No significant difference was observed at 1-year (HR 0.32, 95% CI, 0.081.25

The semaglutide and tirzepatide trials changed that expectation: Semaglutide 2.4 mg once weekly produced average weight loss around 15% at ~68 weeks in adults without diabetes, with a substantial fraction of participants losing 1520% of baseline weight

A prespecified analysis of the FLOW trial evaluated the composite time to the first occurrence of heart failure events (including new onset or worsening heart failure that resulted in an unscheduled hospital admission or urgent visit) or CV death