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Description
GLP-1 restores the intestinal barrier function in DSS-induced colitic mice DSS-induced local and systemic proinflammatory mediators led to the disruption of the intestinal barrier

Furthermore, endotoxemia produced by intestinal dysbiosis may trigger the low-grade inflammation observed in obesity and IR [63]

The researchers also found reduced responses to GLP-1 in both the pancreas and the gut, even though the number of GLP-1 receptors in these tissues remained unchanged

Journal of Psychiatric Research, 102, 207-215
