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A single early injection (1 to 2 days ahead) typically doesn't increase nausea or other side effects because your dose remains the same and your body has time to process the medication

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In addition, patients with PWS have a higher incidence of metabolic complications, such as CVD, T2D, hypertension, and obstructive sleep apnea [5, 14, 15], thus contributing to increased morbidity and mortality in these patients [14, 16]

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