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Not losing weight on a GLP-1
the endocytic adaptor Epsin binds to the ubiquitinated intracellular domain, and the resulting Clathrin-mediated endocytosis exerts a pulling force that exposes the cleavage site in the NRR [[4][4][6][5]]
Weight-loss injections, such as Wegovy and Mounjaro, have transformed how we treat obesity.
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