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Thus, despite there being only modest differences in glycaemic control that was not intensified, incident or worsening nephropathy (progression to macroalbuminuria) was reduced by 39%, with a 44% risk reduction in doubling of serum creatinine
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Consequently, the current study indicates that the degradation rate of GLP-1 differs across species, and that accurate estimation of GLP-1 secretion in rodents (particularly in mice) requires assays that can cope with this
