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She also learned that where she injected the medication mattered

If you are debating whether to increase from 10 mg to 12.5 mg or 15 mg, the additional weight loss is statistically modest

13 This study found that rats treated with exendin-4 had increased endothelial progenitor cells and protein levels of vascular endothelial growth factor receptor-2 (VEGF R2), phosphorylated endothelial nitric oxide synthase (eNOS), matrix metalloproteinase-2 (MMP-2), and transforming growth factor- (TGF-)

These results highlight that injectables generally deliver the greatest effect, while oral tablets and daily injections provide moderate but still meaningful reductions