is glp-1 safe if you don't have diabetes Do The Benefits of Drugs OutWeigh the Negatives? GLP-1 therapies are changing obesity

The researchers suggest that reductions in inflammation and protein production, and improved insulin signaling, may be involved

For example, Wegovy prescribing information states that it is used with a reduced-calorie diet and increased physical activity to help certain adults and adolescents reduce excess body weight and maintain long-term weight reduction

The headline figure that got attention: a 15.9% non-placebo-adjusted weight loss at 32 weeks on 2.4 mg weekly dosing, with no plateau observed at that timepoint

Non-GLP-1 medications are also available to support appetite, cravings, or metabolic function, sometimes used in combination for a more personalized approach