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Description
Athletes who use semaglutide without maintaining rigorous gym discipline and protein intake often experience disappointing results and accelerated muscle loss

10.1016/S2213-8587(19)30249-9 22

Reported outcomes can vary by trial design, population, and estimand, and individual results vary

Key trials like STEP (Semaglutide Treatment Effect in People with obesity) showed 14.9-17.4% weight loss at 68 weeks versus 2.4% on placebo
