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Mitigating Side Effects Several strategies have proven effective for managing adverse events: Starting with lower doses (e.g., 0.5 mg) rather than higher doses Implementing gradual dose escalation with adequate time between increases Maintaining patients at current doses longer when side effects emerge Monitoring and providing supportive care for gastrointestinal symptoms[8] These approaches can significantly improve tolerability and adherence to the medication regimen

Some even suggest that GLP-1 agonists might have the potential to supplant MASH therapy in its entirety

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