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A gene set enrichment analysis (GSEA), based on preranked tumor-regulated genes (according to log2-fold change compared to chow-fed controls), supported activated tumor genes being overrepresented in the HCC S1 subclass (Fig

Nakamura J, Kamiya H, Haneda M, et al

The result is not only significant weight loss but also improved metabolic health

The study showed a 13% reduction in major adverse cardiovascular events (MACE), a composite endpoint for cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke, in patients treated with liraglutide compared with placebo at a mean follow-up of 3.8 years (hazard ratio [HR] 0.87, 95% confidence interval [CI] 0.780.97) and a significant reduction in cardiovascular death (HR 0.78, 95% CI 0.660.93)