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The results showed that BA1b significantly reduced blood glucose and serum insulin levels, promoted secretion of glucose-dependent insulinotropic polypeptide (GIP), and glucagon-like peptide-1 (GLP-1) in diabetic mice

The authors found that the number of GLP-1 expressing cells is consistently reduced at the site of active disease in both mouse models of intestinal inflammation and in CD patients, as confirmed by the single-cell RNA sequencing data