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Results show broad benefits with a reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimers disease and dementia), coagulation disorders, cardiometabolic disorders, infectious illnesses and several respiratory conditions

Consequently, GLP-1 that is secreted by intestinal L-cells is rapidly degraded by dipeptylpeptidase-4 (DPP-4) in the endothelium of the portal circulation and in the liver, as well as by a soluble circulating moiety of DPP-4

Those looking for steady, manageable results

Glucagon-like peptide 1 (GLP-1) based therapies have seen a meteoric rise in popularity (about 300%1 increased use between 2018-2023)