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Rarer ones include gallbladder problems, pancreatitis, and gastroparesis, a chronic stomach condition that can cause serious pain, vomiting, and malnutrition

This rapid reversal upon changing medications strongly suggests that the mechanism was pharmacological rather than psychological, and that different GLP-1 agonists may have different effects on sexual function

GLP-1's roles in the body include: Stimulating insulin secretion from the pancreas in a glucose-dependent manner Suppressing glucagon (which otherwise drives the liver to release stored glucose) Slowing gastric emptying, which prolongs feelings of fullness Signaling satiety centers in the brain to reduce appetite Supporting healthy blood glucose levels already in the normal range GLP-1's challenge is that it has a very short half-life in the bloodstream (typically just 2 minutes) before an enzyme called DPP-4 breaks it down

Healthcare providers should educate patients on storage requirements at the time of prescribing to prevent medication waste and therapeutic failure