glp 1 agonist muscle loss Weight with GLP-1 medicines does not result in a disproportionate loss of mass or function in obese mice and humans: Cell Reports Medicine Muscle loss and GLP-1R agonists
Description
GLP-1R signaling enhances glucose-dependent insulin secretion by activating of G s , upregulating of cAMP, and subsequently activating of PKA (110)
Beyond their role in glucose metabolism, GLP-1 and its receptor agonists have emerged as multifunctional agents with broad cardiometabolic, renal, and immunomodulatory benefits
doi: 10.1001/jamacardio.2020.1966 136 AlorfiNMAlgarniAS
& Schwartz, T
