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Gradually lowering the dose and having a maintenance plan in place can help reduce the risk of regain

For most people, this is when the effect transitions from "I think something might be different" to "I am definitely eating less and it requires no effort." By weeks 4-8, particularly as doses reach 4 mg or higher, the appetite effect is typically well established

Personal Opinion: Protein intake gets underemphasized in most weight loss discussions

Eli Lilly has validated this range as acceptable for clinical use, meaning the medication still delivers enough active compound to produce therapeutic effects
