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There is ongoing work in this area, including elucidating the modulatory effects of liraglutide on the EAT microenvironment (NCT03260881) (Table 3)
We observed a reduction in mesenteric white adipose tissue (WAT) in I-M-150847 treated mice (mean % normalized fat mass, control : 0.2752 0.019% n=5 and upon I-M-150847 treatment: 0
10.3390/biomedicines13010217 115 RamaiteF
Receptor desensitization and tachyphylaxis When receptors are exposed to an agonist continuously, they can become less responsive over time
