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Description
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Patients on GLP-1 injections can lose 15 to 20 percent of their body weight over 12 to 18 months

GLP-1 analogs were administered for 21 days to MC4R KO mice and compared their efficacy

Risk of bias: all four RCTs were rated low risk by RoB2 (with some concerns for open-label outcome ascertainment in three trials, a domain-specific issue that does not alter the overall RoB2 category from low)
