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Similarly, there was no efflux system for [Ser 8 ]GLP-1 to exit the brain other than following the reabsorption of cerebrospinal fluid (CSF)

specializing in weight management, GLP-1 medication nutrition therapy, bariatric surgery, digestive health, and sustainable behavior change Leah Jones, MD Board-certified in Internal Medicine and Obesity Medicine Leah Jones, MD Board-certified in Internal Medicine and Obesity Medicine Katherine Austin, MD, MPH, FAAP, FRCP(C) Board-certified in Pediatrics and Adolescent Medicine Katherine Austin, MD, MPH, FAAP, FRCP(C) Board-certified in Pediatrics and Adolescent Medicine Heather Cecchini, MSN, APRN, ANP-C Board-certified Adult-Primary Care Nurse Practitioner Heather Cecchini, MSN, APRN, ANP-C Board-certified Adult-Primary Care Nurse Practitioner Clete Barrick, MD Board-certified in Internal Medicine and Obesity Medicine Clete Barrick, MD Board-certified in Internal Medicine and Obesity Medicine Caitlin Camill, RDN, CDCES Certified Diabetes Care and Education Specialist

Answer: Semaglutide targets one receptor (GLP-1), tirzepatide targets two (GLP-1 and GIP), and retatrutide targets three (GLP-1, GIP, and glucagon)

The medical practitioner can also recommend physical activities and lifestyle adjustments to help them support their overall health