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Finally, set realistic expectations: some degree of adjustment is normal when starting these medications, and many patients find that energy levels improve as their bodies adapt to the new metabolic state and side effects diminish, typically within the first 48 weeks of treatment

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Blood sugar fluctuations may occur, particularly in patients with diabetes or prediabetes

Spencer Nadolsky about his involvement with Sequence, which eventually became WeightWatchers Clinic: I was the medical director for Sequence (now WeightWatchers Clinic) at the beginning