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Synthetized from cholesterol in the liver, bile acids facilitate formation of micelles in the intestine, promoting absorption of dietary fat (197), but additionally, they are increasingly recognized to act as signaling molecules and receptor ligands (198)

As an alternative to phentermine, the combination of phentermine and topiramate, the active ingredients in Qsymia, may be a suitable option

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"And so I think this becomes for patients much more difficult than it obviously needs to be."