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These findings do not prove GLP-1 medications directly caused every reported symptom, but they do highlight why patients should track changes in energy, digestion, menstrual cycles, temperature sensitivity, mood and vision, and discuss them with a healthcare provider

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The off-label use of semaglutide in treating cocaine dependence remains experimental, with early-stage clinical trials and preclinical evidence supporting its influence on drug cravings [9, 32]

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