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15 An in vitro decidualization model, in which the endometrial stromal cells were exposed to cAMP and progesterone for 4 to 14 days, has been successfully used to advance the understanding of endometrial factors associated with PCOS, particularly by identifying abnormalities in the decidualization process of endometrial stromal cells 19 and noting the decreased expression of stanniocalcin1, 20 a marker of endometrial receptivity

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Each advancement has built upon previous discoveries, with dual agonism outperforming single agonism, and early triple agonist data suggesting even greater potential

Quesada I, Tudur E, Ripoll C, Nadal