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& Creutzfeldt, W

Sitagliptin, the first developed inhibitor, has a triazolopiperazine structure, while vildagliptin and saxagliptin have a cyanopyrrolidine structure

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Regarding the rest of the biomarkers, univariate ANCOVA with BMI adjustment was used with variables fitting a normal distribution and the Mann Whitney U test for those not fitting the normal distribution