maintenance on glp 1 I Started GLP-1 Maintenance... Here's My Survival Strategy GLP-1 Maintenance: What Happens After
Description
362 , 389394 (2002) Xiao, Q., Jeng, W

Summary: No, you do not need to wean off Trulicity, as it does not cause physical dependence or withdrawal symptoms when stopped abruptly
The good news is that you dont necessarily have to stop your medication before surgery

The main enzyme involved, dipeptidyl peptidase-4 (DPP-4) also known as CD26, cleaves off the two N-terminal residues resulting in GLP-1 (9-36 amide) which is inactive or acts as an inhibitor at the GLP-1 receptor (23)
