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Cons of Thigh Injections Potential for Slower Absorption : Some users have reported that the thigh may result in slightly slower absorption of the medication compared to the abdomen

N Engl J Med 387(3):205216 Jensen TL et al (2024) The body weight reducing effects of Tirzepatide in people with and without type 2 diabetes: a review on efficacy and adverse effects
This finding suggests that the primary mechanism of GLP-1RAs in the retina is likely direct neuroprotection