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However, due to its indicated short half-live, GLP-1 peptide is an unattractive therapeutic agent on itself, which stimulated the quest for GLP-1 based compounds with better bioavailability

(2) a composite incidence of MACE (HR 0.95

Susan Akin, a 41-year-old patient at Caron Treatment Centers in Florida, began receiving Zepbound, another GLP-1 medication, for cocaine and alcohol addiction earlier this year

Abstract Glucagon-like peptide-1 (GLP-1) is a 30-amino acid hormone secreted by L cells in the distal ileum, colon, and pancreatic cells, which participates in blood sugar regulation by promoting insulin release, reducing glucagon levels, delaying gastric emptying, increasing satiety, and reducing appetite