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When to Consult Your Doctor Before Taking Pain Relievers Check with your doctor before taking NSAIDs if you have any of the following conditions: kidney disease, liver issues, unmanaged diabetes, high blood pressure, or if you require pain relief for more than 10 days or have a fever lasting over 3 days

Curr Top Med Chem (2019) 19(16):138198

10.1038/nrgastro.2009.148 [DOI] [PubMed] [Google Scholar] 43.Honka H, Salehi M

Going further, another paper that estimated the current and projected costs of overweight and obesity for 161 countries found that by 2060 (relative to 2019), the economic cost of overweight and obesity will increase 15- to 25-fold in low- and middle-income countries, and 4-fold in high-income countries, which will increase obesity-associated costs from 2.19% (in 2019) to 3.29% (in 2060) of the global GDP [24]
