negative effects of glp 1 drugs GI Adverse Glucagon-Like Peptide-1 Receptor Agonists GLP-1R Agonists for Weight Loss

Description

Declines were even more pronounced among households with GLP-1 weight loss users, who decreased food spending six times faster than non-GLP-1 households (-3%)

An observational cohort study involving 168 pregnant women exposed to GLP-1 receptor agonists during the first trimester found a 2.6% prevalence of major birth defects, comparable to 2.3% in the diabetic reference group

Science and Clinical Translation The diverse and interconnected mechanisms of action of GLP-1 receptor agonistsspanning cardiac, vascular, endothelial, platelet, and broad intracellular signaling pathwaysestablish a robust scientific foundation and a clear roadmap for their investigation, clinical trial design, and therapeutic use in medicine