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This review aimed to evaluate the association between PPI-dependent alterations in the intestinal flora and resultant digestive diseases

The specific incretin mimetics that we investigate are semaglutide (brand name Wegovy for weight loss and Ozempic and Rybelsus for type 2 diabetes) and tirzepatide (brand name Zepbound for weight loss and Mounjaro for type 2 diabetes)

5 According to 2023 CDC data, in the United States 40.1 million people have diabetes, with type 2 diabetes representing 90% to 95%, or an estimated 36 38 million people living with type 2 diabetes, making it the most common form of the disease

Most people experience mild to moderate side effects like nausea, vomiting, diarrhea, or constipation, especially when first starting the medication