gip1 vs glp 1 💉 GLP-1 GLP-1/GIP: What's the Difference? You've probably heard about Semaglutide and Tirzepatide — two popular options for medical weight loss — but what actually sets them apart? 🤔 ✨ Semaglutide ( GLP-1 & GIP Agonists |

Today is a bit about where we are now, but also about where we are going, through the lens of the current obstacles that these medications face in the real world

GLP-1R signalling is associated with preventing apoptosis, anti-inflammatory activity and matrix protection

Whilst not explored in detail in the latter project, we observed that the addition of a C-terminal acyl chain further influenced the ability of each ligand to recruit G proteins and -arrestins to the GLP-1R, highlighting this feature as a modifier of GLP-1R efficacy in its own right

Originally developed for type 2 diabetes management, these medications are now widely used for weight loss and obesity treatment