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Moreover, more adults with diabetes in the US have suboptimal glycemic control now compared to 10 years ago [22]

Food and Drug Administration and European Medicines Agency, and UK SmPC hosting via the electronic Medicines Compendium (emc), plus pharmacovigilance-oriented publications using FAERS (and, where available, broader databases)

Adv Ther 42 , 54685480 (2025)

The economic burden is considerable: annual direct healthcare costs attributable to MASLD in the United States and Europe are estimated in the tens of billions of dollars, driven by hospitalizations, liver-related procedures, and management of comorbid conditions [6]