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Eur Heart J 2006;27:23872393

How we love to hate them

Never inject a double dose, and maintain at least 48 hours between injections
39 In the arcuate hypothalamic nucleus, activation of GLP-1 RAs stimulates pro-opiomelanocortin neurons, promoting satiety through -melanocyte-stimulating hormone and inhibiting hunger-associated neurons expressing neuropeptide Y and agouti-related peptide
