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For obesity innovators, 2025 will mark a turning point as we move past peak hype and see the beginning of more conventional competitive dynamics gradually establish themselves in the AOM market

More advanced cases of obesity or diabetes may need higher doses, though even those patients might benefit from starting low and escalating only if needed

Characteristics of Available Injectable GLP-1 Receptor Agonists Although they belong to a single medication class, the approved GLP-1 receptor agonists differ in many ways, including in structure, molecular size, pharmacology, efficacy, and safety (Table 1) (713)

Basic & clinical pharmacology & toxicology , 131 (5), 372379.