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Press Release 26 July 2013
After 56 weeks: Placebo group lost 1.6% of body weight Starting dose (3.75/23 mg) group lost 5.1% of body weight Top dose (15/92 mg) group lost 10.9% of body weight Beyond weight loss, the CONQUER trial showed significant improvements in blood pressure, waist circumference, lipid profiles, glycemic parameters, and inflammatory biomarkers compared to placebo
Comparison of previous meta-analyses Compared to prior studies, this meta-analysis offers several significant advancements in both methodological rigor and clinical insight into the effects of GLP-1 RAs on OSA
They were both first approved to treat type 2 diabetes, and clinical trials also showed that they induced a significant amount of weight loss
