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Common Wegovy side effects include: Upset stomach, nausea, and vomiting Diarrhea or constipation Stomach pain Headache Fatigue Dizziness Gas, bloating, or belching Hypoglycemia (low blood sugar) Heartburn Runny nose or sore throat Redness and irritation at the injection site Wegovy may cause the following serious side effects: Severe allergic reactions Pancreatitis (inflammation of the pancreas) Gallstones and gallbladder problems Kidney problems or kidney failure Changes in vision Increased heart rate Depression or suicidal thoughts Wegovy may cause thyroid tumors, including thyroid cancer, and should not be used by individuals with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)