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Potentially, the fermentation of cellulose and the rise in GLP-1 may have played a role

There have been lawsuits filed against Novo Nordisk, the maker of both drugs, accusing the company of failing to warn patients about the risk of an eye injury known as NAION

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There were no animal studies or even basic physiology suggesting they would be helpful for the cardiovascular system. In 2008, the FDA ordered a series of cardiovascular outcomes trials after two studies suggested lowering blood sugar could be dangerous for the heart in patients with type 2 diabetes, Nauck said