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Incretin-based therapies are commonly used for T2DM because the stimulation of insulin secretion and inhibition of glucagon secretion by these agents occur in a glucose-dependent manner, excluding an intrinsic risk for hypoglycemia (8)

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Mol Pharm (2013) 10(11):39709

Research suggests semaglutide may have enhanced ability to cross the blood-brain barrier compared to liraglutide, leading to stronger effects on the hypothalamic appetite centers
